A REVIEW OF NR1-SITE.COM

Applying this tactic, Kalbaugh et al. assigned affinity and efficacy roles to positions inside the LBDs of the NR1 and NR2A NMDAR subunits. In situ mutation of residues in direct connection with sure ligand affected equally efficacy and affinity, while positions that stabilize the closed cleft conformation with out a direct ligand interaction contr